Acylglycerol Kinase Antikörper (N-Term)

Produktnummer ABIN2774178

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Acylglycerol Kinase in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Rind (Kuh) und Pferd.

Kurzübersicht für Acylglycerol Kinase Antikörper (N-Term) (ABIN2774178)

Target: Acylglycerol Kinase (AGK)

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acylglycerol Kinase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Acylglycerol Kinase Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: AGK Antibody - N-terminal region

Sequenz: KKLLELMENT DVIIVAGGDG TLQEVVTGVL RRTDEATFSK IPIGFIPLGE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGK

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57170-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Acylglycerol Kinase

Target: Acylglycerol Kinase (AGK)

Andere Bezeichnung: AGK

Hintergrund:

Background Information: AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

Gene Name: Acylglycerol kinase

Alternative Symbols: MULK, CATC5, CTRCT38, MTDPS10

Protein Name: Acylglycerol kinase, mitochondrial

Molekulargewicht: 47kDa

Gen-ID: 55750

NCBI Accession: NP_060708

UniProt: Q53H12