Acylglycerol Kinase Antikörper (N-Term)

Produktnummer ABIN2774178

Produktdetails anti-Acylglycerol Kinase Antikörper

Target: Acylglycerol Kinase (AGK)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acylglycerol Kinase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KKLLELMENT DVIIVAGGDG TLQEVVTGVL RRTDEATFSK IPIGFIPLGE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Acylglycerol Kinase

Target: Acylglycerol Kinase (AGK)

Andere Bezeichnung: AGK (AGK Produkte)

Hintergrund: AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: PCSK9, UBC, RNF2, BMI1, PARK2, FBXO6, UBD, CUL3, AGO4, RYK, ICT1, SNX4, PDLIM1, HCK,
Protein Size: 422

Molekulargewicht: 47 kDa

Gen-ID: 55750

NCBI Accession: NM_018238, NP_060708

UniProt: Q53H12