PHYH Antikörper (N-Term)
Kurzübersicht für PHYH Antikörper (N-Term) (ABIN2774157)
Target
Alle PHYH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- PHYH Antibody - N-terminal region
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Sequenz
- TLPEILKYVE CFTGPNIMAM HTMLINKPPD SGKKTSRHPL HQDLHYFPFR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PHYH. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PHYH
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56681-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))
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Andere Bezeichnung
- PHYH
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Hintergrund
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Background Information: This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Name: Phytanoyl-CoA 2-hydroxylase
Alternative Symbols: RD, LN1, PAHX, LNAP1, PHYH1
Protein Name: Phytanoyl-CoA dioxygenase, peroxisomal
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Molekulargewicht
- 39kDa
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Gen-ID
- 5264
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NCBI Accession
- NP_001032626
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UniProt
- O14832
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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