Selenoprotein P Antikörper (N-Term)

Produktnummer ABIN2774140

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Selenoprotein P in WB. Er zeigt eine Reaktivität gegenüber Human und Pferd.

Kurzübersicht für Selenoprotein P Antikörper (N-Term) (ABIN2774140)

Target: Selenoprotein P (SEPP1)

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selenoprotein P Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Selenoprotein P Antikörper

Bindungsspezifität: N-Term

Sequenz: LGLALALCLL PSGGTESQDQ SSLCKQPPAW SIRDQDPMLN SNGSVTVVAL

Homologie: Horse: 85%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SEPP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SEPP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 411 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Selenoprotein P

Target: Selenoprotein P (SEPP1)

Andere Bezeichnung: SEPP1

Hintergrund: SEPP1 is a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space.This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.
Alias Symbols: SELP, SeP
Protein Interaction Partner: EP300, MEOX2, THRA, EGFR,
Protein Size: 411

Molekulargewicht: 46 kDa

Gen-ID: 6414

NCBI Accession: NM_001093726, NP_001087195

UniProt: P49908