ANKRD15 Antikörper (C-Term)

Produktnummer ABIN2774113

Der Kaninchen Polyklonal anti-ANKRD15 Antikörper wird verwendet zum Nachweis von ANKRD15 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für ANKRD15 Antikörper (C-Term) (ABIN2774113)

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ANKRD15 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: KANK1 Antibody - C-terminal region

Sequenz: STALSIALEA GHKDIAVLLY AHVNFAKAQS PGTPRLGRKT SPGPTHRGSF

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KANK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human KANK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55572-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ANKRD15

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Andere Bezeichnung: KANK1

Hintergrund:

Background Information: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5,9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.

Gene Name: KN motif and ankyrin repeat domains 1

Alternative Symbols: KANK, CPSQ2, ANKRD15

Protein Name: KN motif and ankyrin repeat domain-containing protein 1

Molekulargewicht: 36kDa

Gen-ID: 23189

NCBI Accession: NP_001243805

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization