NXT1 Antikörper (N-Term)

Produktnummer ABIN2774091

Der Kaninchen Polyklonal Anti-NXT1-Antikörper wurde für WB validiert. Er ist geeignet, NXT1 in Proben von Maus, Human, Rind (Kuh), Meerschweinchen, Ratte, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für NXT1 Antikörper (N-Term) (ABIN2774091)

Target: NXT1 (NTF2-Related Export Protein 1 (NXT1))

Reaktivität: Maus, Human, Rind (Kuh), Meerschweinchen, Ratte, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NXT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NXT1 Antikörper

Bindungsspezifität: N-Term

Sequenz: GTATLVWNGN AVSGQESLSE FFEMLPSSEF QISVVDCQPV HDEATPSQTT

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against NXT1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NXT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 140 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NXT1

Target: NXT1 (NTF2-Related Export Protein 1 (NXT1))

Andere Bezeichnung: NXT1

Hintergrund: The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
Alias Symbols: MTR2, P15
Protein Interaction Partner: NXF3, PAXIP1, UBC, STAU1, NXF1, DDOST, VPS36, XPO1, RAN, NXF2,
Protein Size: 140

Molekulargewicht: 16 kDa

Gen-ID: 29107

NCBI Accession: NM_013248, NP_037380

UniProt: Q9UKK6