USP21 Antikörper (N-Term)

Produktnummer ABIN2774072

Der Kaninchen Polyklonal anti-USP21 Antikörper wird verwendet zum Nachweis von USP21 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für USP21 Antikörper (N-Term) (ABIN2774072)

Target: USP21 (Ubiquitin Specific Peptidase 21 (USP21))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-USP21 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Usp21 Antibody - N-terminal region

Sequenz: PLPPRPGPPD ERLKKLELGR GRTSGSRPRG PLRADHGVPL PGSPPPAVAL

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Usp21. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Usp21

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54439-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu USP21

Target: USP21 (Ubiquitin Specific Peptidase 21 (USP21))

Andere Bezeichnung: Usp21

Hintergrund:

Background Information: Usp21 deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Usp21 regulates gene expression via histone H2A deubiquitination. It is also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.

Gene Name: ubiquitin specific peptidase 21

Alternative Symbols: Usp, ESTM2, Usp16, Usp23, ESTM28, W53272

Protein Name: Ubiquitin carboxyl-terminal hydrolase 21

Molekulargewicht: 63 kDa

Gen-ID: 30941

NCBI Accession: NP_038947

UniProt: Q9QZL6