CRYGC Antikörper (Middle Region)

Produktnummer ABIN2774014

Der Kaninchen Polyklonal anti-CRYGC Antikörper (ABIN2774014) detektiert spezifisch CRYGC in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Kaninchen, Rind (Kuh), Hund und Pferd.

Kurzübersicht für CRYGC Antikörper (Middle Region) (ABIN2774014)

Target: CRYGC (Crystallin, gamma C (CRYGC))

Reaktivität: Human, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYGC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRYGC Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: CRYGC Antibody - middle region

Sequenz: GLSDSIRSCC LIPQTVSHRL RLYEREDHKG LMMELSEDCP SIQDRFHLSE

Homologie: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CRYGC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRYGC

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52388-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CRYGC

Target: CRYGC (Crystallin, gamma C (CRYGC))

Andere Bezeichnung: CRYGC

Hintergrund:

Background Information: Crystallins are the dominant structural components of the vertebrate eye lens.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Crystallin, gamma C

Alternative Symbols: CCL, CRYG3, CTRCT2

Protein Name: Gamma-crystallin C

Molekulargewicht: 21kDa

Gen-ID: 1420

NCBI Accession: NP_066269

UniProt: P07315