FRS3 Antikörper (Middle Region)

Produktnummer ABIN2774008

Der Kaninchen Polyklonal anti-FRS3 Antikörper (ABIN2774008) detektiert spezifisch FRS3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen und Schwein.

Kurzübersicht für FRS3 Antikörper (Middle Region) (ABIN2774008)

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FRS3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: GFPDGEEDET PLQKPTSTRA AIRSHGSFPV PLTRRRGSPR VFNFDFRRPG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FRS3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FRS3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 492 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FRS3

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Andere Bezeichnung: FRS3

Hintergrund: FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRS2B, FRS2beta, MGC17167, SNT-2, SNT2
Protein Interaction Partner: NOTCH2NL, RFX6, SPERT, ADAMTSL4, SH3KBP1, CD2AP, SPRY2, TRIP6, TCF4, PLSCR1, GATA1, ERBB2, CBL, AES, ELAVL1, RND1, KARS, BMPR2, NTRK2, PRKCI, NTRK1, MAPK1, PTPN11, FGFR1, GRB2,
Protein Size: 492

Molekulargewicht: 54 kDa

Gen-ID: 10817

NCBI Accession: NM_006653, NP_006644

UniProt: O43559