CSK Antikörper (Middle Region)
Kurzübersicht für CSK Antikörper (Middle Region) (ABIN2774001)
Target
Alle CSK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- CSK Antibody - middle region
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Sequenz
- SEDNVAKVSD FGLTKEASST QDTGKLPVKW TAPEALREKK FSTKSDVWSF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CSK. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CSK
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52042-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CSK (C-Src tyrosine Kinase (CSK))
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Andere Bezeichnung
- CSK
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Hintergrund
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Background Information: CSK specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site.CSK can also act on the LYN and FYN kinases.
Gene Name: C-src tyrosine kinase
Alternative Symbols: MGC117393
Protein Name: Tyrosine-protein kinase CSK
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Molekulargewicht
- 51kDa
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Gen-ID
- 1445
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NCBI Accession
- NP_004374
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UniProt
- P41240
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Pathways
- T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
Target
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