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CSK Antikörper (Middle Region)

CSK Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2774001
  • Target Alle CSK Antikörper anzeigen
    CSK (C-Src tyrosine Kinase (CSK))
    Bindungsspezifität
    • 19
    • 16
    • 12
    • 11
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 112
    • 57
    • 45
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd
    Wirt
    • 99
    • 12
    • 3
    Kaninchen
    Klonalität
    • 99
    • 14
    Polyklonal
    Konjugat
    • 54
    • 9
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CSK Antikörper ist unkonjugiert
    Applikation
    • 102
    • 49
    • 26
    • 26
    • 16
    • 15
    • 13
    • 10
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    SEDNVAKVSD FGLTKEASST QDTGKLPVKW TAPEALREKK FSTKSDVWSF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CSK. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CSK
    Top Product
    Discover our top product CSK Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 450 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CSK (C-Src tyrosine Kinase (CSK))
    Andere Bezeichnung
    CSK (CSK Produkte)
    Synonyme
    AW212630 antikoerper, C-terminal Src kinase antikoerper, c-src tyrosine kinase antikoerper, CSK, non-receptor tyrosine kinase antikoerper, CSK antikoerper, Csk antikoerper
    Hintergrund
    CSK specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site.CSK can also act on the LYN and FYN kinases.
    Alias Symbols: MGC117393
    Protein Interaction Partner: UBC, EGFR, TNRC6B, PAG1, RGS16, ZAP70, CD247, CD3E, KHDRBS1, TENC1, FRK, ARRB2, ARRB1, AKT1, GRB2, VCP, ID3, FHL2, SRCIN1, ZNF212, G3BP1, UBASH3B, SHC1, CBL, JUN, ELAVL1, Csk, MAPK15, DOK3, PTPN22, PTPN18, SIT1, TLR3, LAIR1, DOK1, PXN, PLD2, PRKACA, DAB2,
    Protein Size: 450
    Molekulargewicht
    51 kDa
    Gen-ID
    1445
    NCBI Accession
    NM_004383, NP_004374
    UniProt
    P41240
    Pathways
    T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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