CSK Antikörper (Middle Region)
Kurzübersicht für CSK Antikörper (Middle Region) (ABIN2774001)
Target
Alle CSK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- SEDNVAKVSD FGLTKEASST QDTGKLPVKW TAPEALREKK FSTKSDVWSF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CSK. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CSK
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 450 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CSK (C-Src tyrosine Kinase (CSK))
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Andere Bezeichnung
- CSK
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Hintergrund
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CSK specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site.CSK can also act on the LYN and FYN kinases.
Alias Symbols: MGC117393
Protein Interaction Partner: UBC, EGFR, TNRC6B, PAG1, RGS16, ZAP70, CD247, CD3E, KHDRBS1, TENC1, FRK, ARRB2, ARRB1, AKT1, GRB2, VCP, ID3, FHL2, SRCIN1, ZNF212, G3BP1, UBASH3B, SHC1, CBL, JUN, ELAVL1, Csk, MAPK15, DOK3, PTPN22, PTPN18, SIT1, TLR3, LAIR1, DOK1, PXN, PLD2, PRKACA, DAB2,
Protein Size: 450 -
Molekulargewicht
- 51 kDa
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Gen-ID
- 1445
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NCBI Accession
- NM_004383, NP_004374
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UniProt
- P41240
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Pathways
- T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
Target
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