MYCNOS Antikörper (N-Term)

Produktnummer ABIN2773988

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MYCNOS in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MYCNOS Antikörper (N-Term) (ABIN2773988)

Target: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYCNOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MYCNOS Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MYCNOS Antibody - N-terminal region

Sequenz: WGGETDASNP APALTACCAA EREANVEQGL AGRLLLCNYE RRLVRRCKIA

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MYCNOS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51638-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MYCNOS

Target: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Andere Bezeichnung: MYCNOS

Hintergrund:

Background Information: The N-myc oncogene has been implicated in the pathogenesis of a number of human tumors, including childhood neuroblastoma and adult small cell lung cancer. Complementary DNA clones derived from a transcription unit, N-cym, located on the opposite DNA strand to N-myc have been characterized. There is extensive overlap between the 5' ends of the two transcription units. The N-cym gene, which can encode a 109-amino acid protein, is expressed during fetal development, as well as in tumor cell lines containing amplified N-myc loci, where it is expressed at very high levels. Although other examples of overlapping, opposite-strand eukaryotic genes exist, N-myc and N-cym are unique in that they appear to be coregulated in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid. This coregulation suggests that their protein products may be functionally interrelated during normal development and oncogenesis.

Gene Name: MYCN opposite strand/antisense RNA (non-protein coding)

Alternative Symbols: NCYM, NYCM, N-CYM, MYCN-AS1

Protein Name: N-cym protein

Molekulargewicht: 12kDa

Gen-ID: 10408

NCBI Accession: NP_006307

UniProt: P40205