Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MYCNOS Antikörper (N-Term)

MYCNOS Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2773988
  • Target Alle MYCNOS Produkte
    MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))
    Bindungsspezifität
    N-Term
    Reaktivität
    Human
    Wirt
    • 9
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYCNOS Antikörper ist unkonjugiert
    Applikation
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    WGGETDASNP APALTACCAA EREANVEQGL AGRLLLCNYE RRLVRRCKIA
    Homologie
    Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MYCNOS. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 109 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))
    Andere Bezeichnung
    MYCNOS (MYCNOS Produkte)
    Synonyme
    MYCN-AS1 antikoerper, NCYM antikoerper, NYCM antikoerper, MYCN opposite strand antikoerper, MYCNOS antikoerper
    Hintergrund
    The N-myc oncogene has been implicated in the pathogenesis of a number of human tumors, including childhood neuroblastoma and adult small cell lung cancer. Complementary DNA clones derived from a transcription unit, N-cym, located on the opposite DNA strand to N-myc have been characterized. There is extensive overlap between the 5' ends of the two transcription units. The N-cym gene, which can encode a 109-amino acid protein, is expressed during fetal development, as well as in tumor cell lines containing amplified N-myc loci, where it is expressed at very high levels. Although other examples of overlapping, opposite-strand eukaryotic genes exist, N-myc and N-cym are unique in that they appear to be coregulated in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid. This coregulation suggests that their protein products may be functionally interrelated during normal development and oncogenesis.
    Alias Symbols: NCYM, NYCM, MYCN-AS1
    Protein Size: 109
    Molekulargewicht
    12 kDa
    Gen-ID
    10408
    NCBI Accession
    NM_006316, NP_006307
    UniProt
    P40205
Sie sind hier:
Kundenservice