NPRL2 Antikörper (N-Term)
Kurzübersicht für NPRL2 Antikörper (N-Term) (ABIN2773969)
Target
Alle NPRL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- N-Term
- 
                                            Sequenz
- MGSGCRIECI FFSEFHPTLG PKITYQVPED FISRELFDTV QVYIITKPEL
- 
                                            Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 
                                            Produktmerkmale
- This is a rabbit polyclonal antibody against TUSC4. It was validated on Western Blot using a cell lysate as a positive control.
- 
                                            Aufreinigung
- Affinity Purified
- 
                                            Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TUSC4
 
- 
                                            
- 
    
- 
    - 
                                            Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- 
                                            Kommentare
- 
                        Antigen size: 380 AA 
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- Lot specific
- 
                                            Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Handhabung
- Avoid repeated freeze-thaw cycles.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
- 
                                            
- 
    - 
                                            : "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..."    in: Molecular systems biology, Vol. 3, pp. 89, (2007)         (PubMed).        
 
 
- 
                                            : "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..."    in: Molecular systems biology, Vol. 3, pp. 89, (2007)         (PubMed).        
- 
    - NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
- 
                                            Andere Bezeichnung
- TUSC4
- 
                                            Hintergrund
- 
                        TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
 Alias Symbols: NPR2L, NPRL2, NPR2, TUSC4
 Protein Interaction Partner: UBC, HSP90AA1, CDKN1A, ANXA7, NPRL3, UBE2M, PRKAR1A,
 Protein Size: 380
- 
                                            Molekulargewicht
- 44 kDa
- 
                                            Gen-ID
- 10641
- 
                                            NCBI Accession
- NM_006545, NP_006536
- 
                                            UniProt
- Q8WTW4
 Target
- 
                    
 
                                     
                                     
                                    