PRTFDC1 Antikörper (Middle Region)

Produktnummer ABIN2773930

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-PRTFDC1 Antikörper wird verwendet zum Nachweis von PRTFDC1 in Proben von Human, Ratte, Schwein, Pferd, Kaninchen, Hund und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für PRTFDC1 Antikörper (Middle Region) (ABIN2773930)

Target: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Reaktivität: Human, Ratte, Schwein, Pferd, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRTFDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRTFDC1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: PRTFDC1 Antibody - middle region

Sequenz: MKALLSNIEK YKPNMIKVAS LLVKRTSRSD GFRPDYAGFE IPNLFVVGYA

Homologie: Dog: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 77%, Rat: 92%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against PRTFDC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRTFDC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48854-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PRTFDC1 Antikörper (ABIN2773930)

Suzuki, Imoto, Pimkhaokham, Nakagawa, Kamata, Kozaki, Amagasa, Inazawa: "PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." in: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).

Details zu PRTFDC1

Target: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Andere Bezeichnung: PRTFDC1

Hintergrund:

Background Information: PRTFDC1 belongs to the purine/pyrimidine phosphoribosyltransferase family. Epigenetic silencing of PRTFDC1 by hypermethylation of the CpG islands leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis.

Gene Name: Phosphoribosyl transferase domain containing 1

Alternative Symbols: HHGP

Protein Name: Phosphoribosyltransferase domain-containing protein 1

Molekulargewicht: 26kDa

Gen-ID: 56952

NCBI Accession: NP_064585

UniProt: Q9NRG1

Pathways: Ribonucleoside Biosynthetic Process