Peroxiredoxin 1 Antikörper (N-Term)

Produktnummer ABIN2773920

Der Kaninchen Polyklonal anti-Peroxiredoxin 1 Antikörper wird verwendet zum Nachweis von Peroxiredoxin 1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC.

Kurzübersicht für Peroxiredoxin 1 Antikörper (N-Term) (ABIN2773920)

Target: Peroxiredoxin 1 (PRDX1)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Peroxiredoxin 1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PRDX1 Antibody - N-terminal region

Sequenz: SSGNAKIGHP APNFKATAVM PDGQFKDISL SDYKGKYVVF FFYPLDFTFV

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PRDX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48454-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Andere Bezeichnung: PRDX1

Hintergrund:

Background Information: PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.

Gene Name: Peroxiredoxin 1

Alternative Symbols: PAG, PAGA, PAGB, PRX1, PRXI, MSP23, NKEFA, TDPX2, NKEF-A

Protein Name: Peroxiredoxin-1

Molekulargewicht: 22kDa

Gen-ID: 5052

NCBI Accession: NP_002565

UniProt: Q06830

Pathways: p53 Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events