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Peroxiredoxin 1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-Peroxiredoxin 1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Peroxiredoxin 1 in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen und Zebrafisch (Danio rerio) zu detektieren.
Produktnummer ABIN2773920

Kurzübersicht für Peroxiredoxin 1 Antikörper (N-Term) (ABIN2773920)

Target

Alle Peroxiredoxin 1 (PRDX1) Antikörper anzeigen
Peroxiredoxin 1 (PRDX1)

Reaktivität

  • 71
  • 48
  • 37
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt

  • 74
  • 12
  • 1
Kaninchen

Klonalität

  • 70
  • 16
Polyklonal

Konjugat

  • 45
  • 10
  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Peroxiredoxin 1 Antikörper ist unkonjugiert

Applikation

  • 71
  • 37
  • 24
  • 23
  • 20
  • 20
  • 17
  • 14
  • 13
  • 9
  • 3
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 22
    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    SSGNAKIGHP APNFKATAVM PDGQFKDISL SDYKGKYVVF FFYPLDFTFV

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PRDX1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 199 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    Peroxiredoxin 1 (PRDX1)

    Andere Bezeichnung

    PRDX1

    Hintergrund

    PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.
    Alias Symbols: MSP23, NKEFA, PAG, PAGA, PAGB, PRX1, TDPX2, PRXI
    Protein Interaction Partner: FUS, UBC, MDM2, RPA3, RPA2, RPA1, SUZ12, CACYBP, HECTD1, PRDX2, PRKDC, PPP2R5D, METTL1, PARK2, YWHAQ, VHL, EGFR, CDK2, RAD52, MPG, US3, SH2D1B, LUC7L, HCVgp1, PRDX4, IQCB1, BTRC, UBL4A, VCAM1, SMARCD1, FN1, DAB2, ADH5, ABL1, MYD88, MYC, ITGA4, TIPIN, EIF4
    Protein Size: 199

    Molekulargewicht

    22 kDa

    Gen-ID

    5052

    NCBI Accession

    NM_002574, NP_002565

    UniProt

    Q06830

    Pathways

    p53 Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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