ST14 Antikörper (C-Term)

Produktnummer ABIN2773910

Dieses Anti-ST14-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ST14 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schwein und Kaninchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ST14 Antikörper (C-Term) (ABIN2773910)

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ST14 Antikörper

Bindungsspezifität: C-Term

Sequenz: SHVFPAGKAI WVTGWGHTQY GGTGALILQK GEIRVINQTT CENLLPQQIT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ST14. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ST14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 855 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ST14 Antikörper (ABIN2773910)

Landova Sulcova, Zahradnicek, Dumkova, Dosedelova, Krivanek, Hampl, Kavkova, Zikmund, Gregorovicova, Sedmera, Kaiser, Tucker, Buchtova: "Developmental mechanisms driving complex tooth shape in reptiles." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).

Details zu ST14

Target: ST14 (Suppression of Tumorigenicity 14 (ST14))

Andere Bezeichnung: ST14

Hintergrund: ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Alias Symbols: HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, TADG-15, TADG15, TMPRSS14
Protein Interaction Partner: UBC, RGS16, PDGFC, CDCP1, SPINT1, F2RL1, PLAU, HGF,
Protein Size: 855

Molekulargewicht: 95 kDa

Gen-ID: 6768

NCBI Accession: NM_021978

UniProt: Q9Y5Y6