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NSDHL Antikörper (Middle Region)

Dieses Anti-NSDHL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NSDHL in WB. Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen und Zebrafisch (Danio rerio).
Produktnummer ABIN2773893

Kurzübersicht für NSDHL Antikörper (Middle Region) (ABIN2773893)

Target

Alle NSDHL Antikörper anzeigen
NSDHL (NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL))

Reaktivität

  • 24
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio)

Wirt

  • 20
  • 4
Kaninchen

Klonalität

  • 17
  • 7
Polyklonal

Konjugat

  • 20
  • 2
  • 1
  • 1
Dieser NSDHL Antikörper ist unkonjugiert

Applikation

  • 20
  • 12
  • 8
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    RAVLGANDPE KNFLTTAIRP HGIFGPRDPQ LVPILIEAAR NGKMKFVIGN

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against NSDHL. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human NSDHL
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 373 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    NSDHL (NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL))

    Andere Bezeichnung

    NSDHL

    Hintergrund

    NSDHL is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in NSDHL gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males.The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
    Alias Symbols: H105E3, XAP104, SDR31E1
    Protein Interaction Partner: UBC, FUS, SUMO3,
    Protein Size: 373

    Molekulargewicht

    42 kDa

    Gen-ID

    50814

    NCBI Accession

    NM_015922, NP_057006

    UniProt

    Q15738
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