ICMT Antikörper (Middle Region)

Produktnummer ABIN2773889

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-ICMT Antikörper (ABIN2773889) detektiert spezifisch ICMT in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd und Saccharomyces cerevisiae.

Kurzübersicht für ICMT Antikörper (Middle Region) (ABIN2773889)

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ICMT Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: ICMT Antibody - middle region

Sequenz: GSNFNHVVQN EKSDTHTLVT SGVYAWFRHP SYVGWFYWSI GTQVMLCNPI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ICMT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ICMT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46894-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ICMT Antikörper (ABIN2773889)

Nuthalapaty, Lu, Ramin, Nuthalapaty, Ramin, Ramsey: "Is there a preferred gestational age threshold of viability?: a survey of maternal-fetal medicine providers." in: The journal of maternal-fetal & neonatal medicine, Vol. 20, Issue 4, pp. 293-7, (2007) (PubMed).

Details zu ICMT

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Andere Bezeichnung: ICMT

Hintergrund:

Background Information: ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

Gene Name: Isoprenylcysteine carboxyl methyltransferase

Alternative Symbols: PCMT, PPMT, PCCMT, HSTE14, MST098, MSTP098

Protein Name: Protein-S-isoprenylcysteine O-methyltransferase

Molekulargewicht: 32kDa

Gen-ID: 23463

NCBI Accession: NP_036537

UniProt: O60725