ICMT Antikörper (Middle Region)

Produktnummer ABIN2773889

Produktdetails anti-ICMT Antikörper

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GSNFNHVVQN EKSDTHTLVT SGVYAWFRHP SYVGWFYWSI GTQVMLCNPI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ICMT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ICMT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 284 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ICMT Antikörper (ABIN2773889)

Nuthalapaty, Lu, Ramin, Nuthalapaty, Ramin, Ramsey: "Is there a preferred gestational age threshold of viability?: a survey of maternal-fetal medicine providers." in: The journal of maternal-fetal & neonatal medicine, Vol. 20, Issue 4, pp. 293-7, (2007) (PubMed).

Details zu ICMT

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Andere Bezeichnung: ICMT (ICMT Produkte)

Hintergrund: ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
Alias Symbols: HSTE14, MGC39955, MST098, MSTP098, PCCMT, PCMT, PPMT
Protein Interaction Partner: ELAVL1, UBC, RAC2, RAC1, HRAS, RHOA,
Protein Size: 284

Molekulargewicht: 32 kDa

Gen-ID: 23463

NCBI Accession: NM_012405, NP_036537

UniProt: O60725