TMEM48 Antikörper (Middle Region)

Produktnummer ABIN2773878

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-TMEM48 Antikörper (ABIN2773878) detektiert spezifisch TMEM48 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für TMEM48 Antikörper (Middle Region) (ABIN2773878)

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM48 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TMEM48 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TMEM48 Antibody - middle region

Sequenz: PPIIKYLALQ DLMLLSQYSP SRRQEVFSLS QPGGHPHNWT AISRECLNLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TMEM48. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM48

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46268-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TMEM48 Antikörper (ABIN2773878)

Tarazón, Rivera, Roselló-Lletí, Molina-Navarro, Sánchez-Lázaro, España, Montero, Lago, González-Juanatey, Portolés: "Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes." in: PLoS ONE, Vol. 7, Issue 11, pp. e48957, (2012) (PubMed).

Details zu TMEM48

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Andere Bezeichnung: TMEM48

Hintergrund:

Background Information: TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.

Gene Name: Transmembrane protein 48

Alternative Symbols: NET3, TMEM48

Protein Name: Nucleoporin NDC1

Molekulargewicht: 76 kDa

Gen-ID: 55706

NCBI Accession: NP_060557

UniProt: Q9BTX1