TMEM48 Antikörper (Middle Region)

Produktnummer ABIN2773878

Produktdetails anti-TMEM48 Antikörper

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM48 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PPIIKYLALQ DLMLLSQYSP SRRQEVFSLS QPGGHPHNWT AISRECLNLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TMEM48. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM48

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 674 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TMEM48 Antikörper (ABIN2773878)

Tarazón, Rivera, Roselló-Lletí, Molina-Navarro, Sánchez-Lázaro, España, Montero, Lago, González-Juanatey, Portolés: "Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes." in: PLoS ONE, Vol. 7, Issue 11, pp. e48957, (2012) (PubMed).

Details zu TMEM48

Target: TMEM48 (Transmembrane Protein 48 (TMEM48))

Andere Bezeichnung: TMEM48 (TMEM48 Produkte)

Synonyme: 2810475A17Rik antikoerper, AI450313 antikoerper, Tmem48 antikoerper, NET3 antikoerper, TMEM48 antikoerper, tmem48 antikoerper, wu:fk93f04 antikoerper, zgc:55636 antikoerper, Xndr antikoerper, NDC1 transmembrane nucleoporin antikoerper, NDC1 transmembrane nucleoporin S homeolog antikoerper, Xrcc1 N-terminal domain containing 1 antikoerper, Ndc1 antikoerper, NDC1 antikoerper, ndc1 antikoerper, ndc1.S antikoerper, Xndc1 antikoerper

Hintergrund: TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
Alias Symbols: FLJ10407, FLJ12556, FLJ34120, NDC1, RP4-654H19.1, NET3, TMEM48
Protein Interaction Partner: UBC, Ndc1, NUP93,
Protein Size: 674

Molekulargewicht: 76 kDa

Gen-ID: 55706

NCBI Accession: NM_018087, NP_060557

UniProt: Q9BTX1