RANBP1 Antikörper (C-Term)

Produktnummer ABIN2773873

Der Kaninchen Polyklonal anti-RANBP1 Antikörper wird verwendet zum Nachweis von RANBP1 in Proben von Human, Rind (Kuh), Pferd und Saccharomyces cerevisiae. Er wurde validiert für WB.

Kurzübersicht für RANBP1 Antikörper (C-Term) (ABIN2773873)

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reaktivität: Human, Rind (Kuh), Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RANBP1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: RANBP1 Antibody - C-terminal region

Sequenz: KFEECRKEIE EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ

Homologie: Cow: 79%, Horse: 79%, Human: 100%, Yeast: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against RANBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RANBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46083-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RANBP1

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Andere Bezeichnung: RANBP1

Hintergrund:

Background Information: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: RAN binding protein 1

Alternative Symbols: HTF9A

Protein Name: Ran-specific GTPase-activating protein

Molekulargewicht: 23kDa

Gen-ID: 5902

NCBI Accession: NP_002873

UniProt: P43487