RANBP1 Antikörper (C-Term)

Produktnummer ABIN2773873

Der Kaninchen Polyklonal Anti-RANBP1-Antikörper wurde für WB validiert. Er ist geeignet, RANBP1 in Proben von Human, Rind (Kuh), Pferd und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für RANBP1 Antikörper (C-Term) (ABIN2773873)

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reaktivität: Human, Rind (Kuh), Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RANBP1 Antikörper

Bindungsspezifität: C-Term

Sequenz: KFEECRKEIE EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ

Homologie: Cow: 79%, Horse: 79%, Human: 100%, Yeast: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against RANBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RANBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 201 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RANBP1

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Andere Bezeichnung: RANBP1

Hintergrund: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC88701, HTF9A
Protein Interaction Partner: UBC, SUMO1, MDM2, CHMP4A, PLS3, IDH1, DCK, EGFR, PTMA, RAN, rna1, XPO1, vpu, VCAM1, FN1, CFTR, HNF1A, KPNB1, RCC1, C18orf8, UBD, ELAVL1, Ranbp2, RANGRF, CD93, MPG,
Protein Size: 201

Molekulargewicht: 23 kDa

Gen-ID: 5902

NCBI Accession: NM_002882, NP_002873

UniProt: P43487