MAP4K1 Antikörper (N-Term)
Kurzübersicht für MAP4K1 Antikörper (N-Term) (ABIN2773872)
Target
Alle MAP4K1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- VHPLRVLFLM TKSGYQPPRL KEKGKWSAAF HNFIKVTLTK SPKKRPSATK
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MAP4K1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 821 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
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Andere Bezeichnung
- MAP4K1
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Hintergrund
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MAP4K1 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K1 may play a role in hematopoietic lineage decisions and growth regulation.
Alias Symbols: HPK1
Protein Interaction Partner: FBXW7, FBXW8, MAP4K1, UBC, SKP1, PPP4C, RBX1, CUL7, TMEM101, HSP90AA1, NCK1, LRRK1, SPRY1, GRAP2, COPS5, DBNL, DAPP1, BLNK, MAP3K7, LAT, CRKL, LCP2, HCLS1, CASP3, SHC1, SYK, MAP3K11, ABL1, LYN, CRK, EGFR, GRB2,
Protein Size: 821 -
Molekulargewicht
- 90 kDa
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Gen-ID
- 11184
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NCBI Accession
- NM_001042600, NP_001036065
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UniProt
- A8MWC4
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Pathways
- T-Zell Rezeptor Signalweg, Signaling of Hepatocyte Growth Factor Receptor
Target
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