CD200R1 Antikörper (N-Term)
Kurzübersicht für CD200R1 Antikörper (N-Term) (ABIN2764056)
Target
Alle CD200R1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Kreuzreaktivität
- Human
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Produktmerkmale
- Ox2r, Hypocretin receptor type 2,As first published in 1998 by Sakurai et al, the initial neuropeptides Orexin A and Orexin B were shown to be important in the regulation of appetite. Continued research now suggests that these peptides also influence a wide range of physiological and behavioral processes such as increased EFG arousal and wakefulness and locomotor activity. In addition to the orexins , two G-protein coupled receptors, designated orexin receptor-1 and orexin receptor-2, have been identified which presumably mediate the signaling events from these neuropeptides1. Recently orexin receptors have been found to activate extracellular signal-regulated kinases in CHO cells, namely ERK phosporylation, through Ca2+ influx..2. Further studies seem to indicate a mechanism for orexin receptor mediated cell death and suggest a pathway from GPCRs to apoptosis throughthe MAPK pathways.3
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Aufreinigung
- Antigen Immunoaffiinity Purification
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Immunogen
- Synthetic peptide madde to recombinant Human Orexin Receptor Type 2
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Isotyp
- IgG
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Applikationshinweise
- Optimal concentration should be evaluated by serial dilutions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Affinity purified polyclonal antibody provided as solution in phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CD200R1 (CD200 Receptor 1 (CD200R1))
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Andere Bezeichnung
- Orexin Receptor-2
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UniProt
- O43614
Target
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