FBLN3 Antikörper

Produktnummer ABIN2763849

Dieses Anti-FBLN3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FBLN3 in WB, IHC und EIA. Geeignet für Human.

Kurzübersicht für FBLN3 Antikörper (ABIN2763849)

Target: FBLN3 (Fibulin 3 (FBLN3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBLN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Enzyme Immunoassay (EIA)

Produktdetails anti-FBLN3 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, Fibulin-like protein, EFEMP1,Fibulin-1 is a modular glycoprotein component of elastic extracellular matrix fibers, basement membranes and blood. It can bind calcium, Fibronectin, Laminin, Nidogen and Fibrinogen. Estrogen exposure to ovarian cancer cell lines can upregulate Fibulin-1. Fibulin-2 is abundant in heart, placenta and ovarian tissue and binds several components of the extracelllar matrix including aggrecan, versican and brevican. Fibulin-3, also known as EFEMP1, is a secreted protein. Defects in the gene for Fibulin-3 cause the autosomal dominant disease Doyne honeycomb retinal dystrophy (DHRD, also known as malattia leventinese) which is characterized by yellow-white deposits (drusen) that accumulate under the retinal pigment epithelium. Fibulin-3 is not present at the site of drusen formation in normal eyes. Fibulin-5 is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion.

Aufreinigung: Antigen Immunoaffiinity Purification

Immunogen: Synthetic peptide derived from human fibulin-3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu FBLN3

Target: FBLN3 (Fibulin 3 (FBLN3))

Andere Bezeichnung: Fibulin-3

UniProt: Q12805

Pathways: EGFR Signaling Pathway