CHMP5 Antikörper (AA 1-219) (FITC)

Produktnummer ABIN2755406

Dieses Anti-CHMP5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHMP5 in ELISA. Geeignet für Human.

Kurzübersicht für CHMP5 Antikörper (AA 1-219) (FITC) (ABIN2755406)

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHMP5 Antikörper ist konjugiert mit FITC

Applikation: ELISA

Produktdetails anti-CHMP5 Antikörper (FITC)

Bindungsspezifität: AA 1-219

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Charged multivesicular body protein 5 protein (1-219AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CHMP5

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Andere Bezeichnung: CHMP5

Hintergrund:

Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.

Aliases: apoptosis-related protein PNAS-2 antibody, C9orf83 antibody, CGI 34 antibody, Charged multivesicular body protein 5 antibody, CHMP 5 antibody, CHMP family, member 5 antibody, chmp5 antibody, CHMP5_HUMAN antibody, Chromatin modifying protein 5 antibody, Chromatin-modifying protein 5 antibody, Chromosome 9 open reading frame 83 antibody, HGNC:26942 antibody, HSPC177 antibody, hVps60 antibody, PNAS 2 antibody, SNF7 domain containing protein 2 antibody, SNF7 domain-containing protein 2 antibody, SNF7DC2 antibody, Vacuolar protein sorting 60 antibody, Vacuolar protein sorting-associated protein 60 antibody, Vps60 antibody

UniProt: Q9NZZ3