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CD68 Antikörper (PE)

Dieses Anti-CD68-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD68 in FACS. Geeignet für Human. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.
Produktnummer ABIN2749210

Kurzübersicht für CD68 Antikörper (PE) (ABIN2749210)

Target

Alle CD68 Antikörper anzeigen
CD68 (CD68 Molecule (CD68))

Reaktivität

  • 218
  • 70
  • 41
  • 35
  • 28
  • 18
  • 8
  • 5
  • 2
  • 2
  • 1
Human

Wirt

  • 150
  • 94
  • 19
  • 1
Maus

Klonalität

  • 187
  • 72
  • 1
Monoklonal

Konjugat

  • 109
  • 19
  • 15
  • 11
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD68 Antikörper ist konjugiert mit PE

Applikation

  • 118
  • 110
  • 103
  • 70
  • 67
  • 36
  • 34
  • 34
  • 22
  • 20
  • 11
  • 9
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

Y1-82A
  • Verwendungszweck

    Anti-Hu CD68 PE

    Spezifität

    The mouse monoclonal antibody Y1/82A recognizes CD68 (LAMP4), a 110 kDa glycoprotein expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells.

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    Lysosomal contents of lung macrophages

    Isotyp

    IgG2b
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Yamagami, Yokoo, Amano, Ebihara: "Characterization of bone marrow derived cells in the substantia propria of the human conjunctiva." in: Investigative ophthalmology & visual science, Vol. 48, Issue 10, pp. 4476-81, (2007) (PubMed).

    Mack, Tucker, Sokol, Karrer, Kotzin, Whitington, Miller: "Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation." in: Pediatric research, Vol. 56, Issue 1, pp. 79-87, (2004) (PubMed).

    Ulanova, Tarkowski, Hahn-Zoric, Hanson: "The Common vaccine adjuvant aluminum hydroxide up-regulates accessory properties of human monocytes via an interleukin-4-dependent mechanism." in: Infection and immunity, Vol. 69, Issue 2, pp. 1151-9, (2001) (PubMed).

    Doussis, Gatter, Mason: "CD68 reactivity of non-macrophage derived tumours in cytological specimens." in: Journal of clinical pathology, Vol. 46, Issue 4, pp. 334-6, (1993) (PubMed).

    Holness, Simmons: "Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins." in: Blood, Vol. 81, Issue 6, pp. 1607-13, (1993) (PubMed).

  • Target

    CD68 (CD68 Molecule (CD68))

    Andere Bezeichnung

    CD68

    Hintergrund

    CD68 Molecule,CD68 (also known as LAMP4 or SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms).,GP110, LAMP4, SCARD1

    Gen-ID

    968

    UniProt

    P34810
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