PCLO Antikörper (PE)

Produktnummer ABIN2749163

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PCLO in ICFC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PCLO Antikörper (PE) (ABIN2749163)

Target: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PCLO Antikörper ist konjugiert mit PE

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: PCLO-01

Produktdetails anti-PCLO Antikörper (PE)

Verwendungszweck: Anti-PCLO PE

Spezifität: The mouse monoclonal antibody PCLO-01 recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human recombinant PCLO protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu PCLO

Target: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Andere Bezeichnung: PCLO

Hintergrund: Piccolo presynaptic cytomatrix protein,PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.,ACZ, PCH3, piccolo, aczonin

Gen-ID: 27445

UniProt: Q9Y6V0

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis