LARGE1 (AA 35-142) Antikörper (PE)
-
- Target
- LARGE1
- Bindungsspezifität
- AA 35-142
- Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- PE
-
Applikation
- Flow Cytometry (FACS)
- Spezifität
- The mouse monoclonal antibody LARGE-02 recognizes human LARGE1, a glycosyltransferase expressed mainly in the Golgi apparatus. Crossreactivity with LARGE2 was not determined.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Recombinant fragment of human LARGE1 (amino acids 35-142)
- Klon
- LARGE-02
- Isotyp
- IgG2b
-
anti-LARGE1 (AA 35-142) antibody
Reaktivität: Human FACS, WB Wirt: Maus Monoclonal LARGE-02 unconjugated
anti-LARGE1 (AA 35-142) antibody (PE)Reaktivität: Human FACS, WB Wirt: Maus Monoclonal PE
-
- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
- Kommentare
-
The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate was purified by size-exclusion chromatography.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.1 mg/mL
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
- Target
- LARGE1
- Hintergrund
- LARGE xylosyl- and glucuronyltransferase 1,LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.,Xysosyl- and glucosyl transferase 1
- Gen-ID
- 9215
- UniProt
- O95461
-
