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CD81 Antikörper (APC)

Der Maus Monoklonal Anti-CD81-Antikörper wurde für FACS validiert. Er ist geeignet, CD81 in Proben von Human, Kaninchen und Cat zu detektieren. Es sind 4+ Publikationen verfügbar.
Produktnummer ABIN2749137

Kurzübersicht für CD81 Antikörper (APC) (ABIN2749137)

Target

Alle CD81 Antikörper anzeigen
CD81

Reaktivität

  • 208
  • 143
  • 81
  • 25
  • 25
  • 25
  • 17
  • 16
  • 9
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Kaninchen, Cat

Wirt

  • 118
  • 93
  • 41
  • 11
  • 3
  • 3
  • 1
  • 1
Maus

Klonalität

  • 207
  • 56
  • 4
Monoklonal

Konjugat

  • 112
  • 22
  • 19
  • 18
  • 9
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD81 Antikörper ist konjugiert mit APC

Applikation

  • 197
  • 105
  • 85
  • 52
  • 49
  • 41
  • 35
  • 30
  • 30
  • 26
  • 22
  • 14
  • 14
  • 13
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

M38
  • Verwendungszweck

    Anti-Hu CD81 APC

    Spezifität

    The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

    Kreuzreaktivität (Details)

    Human, Feline (Cat), Rabbit

    Aufreinigung

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    MOLT-4 (human T-ALL cell line)

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

    Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

    Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

    Fukudome, Furuse, Imai, Nishimura, Takagi, Hinuma, Yoshie et al.: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." in: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).

  • Target

    CD81

    Andere Bezeichnung

    CD81

    Hintergrund

    CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

    Gen-ID

    975

    UniProt

    P60033

    Pathways

    Inositol Metabolic Process, Hepatitis C
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