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SLAMF1 Antikörper (PE)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SLAMF1 in FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN2749109

Kurzübersicht für SLAMF1 Antikörper (PE) (ABIN2749109)

Target

Alle SLAMF1 Antikörper anzeigen
SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reaktivität

  • 70
  • 53
  • 22
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 69
  • 26
  • 19
  • 1
Maus

Klonalität

  • 68
  • 43
  • 2
Monoklonal

Konjugat

  • 46
  • 12
  • 10
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SLAMF1 Antikörper ist konjugiert mit PE

Applikation

  • 50
  • 45
  • 28
  • 17
  • 14
  • 13
  • 13
  • 10
  • 7
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

SLAM-4
  • Verwendungszweck

    Anti-Hu CD150 PE

    Spezifität

    The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    Human CD150-transfected 300.19 cells

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

    Romero, Benítez, March, Vilella, Miralpeix, Engel: "Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)." in: Tissue antigens, Vol. 64, Issue 2, pp. 132-44, (2004) (PubMed).

  • Target

    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

    Andere Bezeichnung

    CD150

    Hintergrund

    Signaling lymphocytic activation molecule family m,CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.,SLAM, SLAMF1

    Gen-ID

    6504

    UniProt

    Q13291
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