PDE2A Antikörper (C-Term)

Produktnummer ABIN2747086

Dieser Anti-PDE2A Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PDE2A in WB, ELISA, IHC, IF, IP, CM, ICC und FRET. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 27+ Publikationen zitiert.

Kurzübersicht für PDE2A Antikörper (C-Term) (ABIN2747086)

Target: PDE2A (phosphodiesterase 2A, CGMP-Stimulated (PDE2A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Confocal Microscopy (CM), Immunocytochemistry (ICC), Fluorescence Resonance Energy Transfer Microscopy (FRET)

Produktdetails anti-PDE2A Antikörper

Bindungsspezifität: AA 875-925, C-Term

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide taken within amino acid region 875-925 on human PDE2A protein. Will label all PD2A variants.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 μg/μL

Referenzen für anti-PDE2A Antikörper (ABIN2747086)

Fields, Koschinski, Zaccolo: "Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes." in: Cellular signalling, Vol. 28, Issue 7, pp. 725-32, (2017) (PubMed).

Pathak, Agostino, Bishara, Capell, Fisher, Hegde, Ibrahim, Pilarzyk, Sabin, Tuczkewycz, Wilson, Kelly: "PDE11A negatively regulates lithium responsivity." in: Molecular psychiatry, Vol. 22, Issue 12, pp. 1714-1724, (2017) (PubMed).

Vettel, Lindner, Dewenter, Lorenz, Schanbacher, Riedel, Lämmle, Meinecke, Mason, Sossalla, Geerts, Hoffmann, Wunder, Brunner, Wieland, Mehel, Karam, Lechêne, Leroy, Vandecasteele, Wagner et al.: "Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction." in: Circulation research, Vol. 120, Issue 1, pp. 120-132, (2017) (PubMed).

Sprenger, Perera, Steinbrecher, Lehnart, Maier, Hasenfuss, Nikolaev: "In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease." in: Nature communications, Vol. 6, pp. 6965, (2016) (PubMed).

Hiramoto, Murata, Shimizu, Morita, Inui, Manganiello, Tagawa, Arai: "Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells." in: Cellular signalling, Vol. 26, Issue 9, pp. 1807-17, (2015) (PubMed).

Rentsendorj, DAlessio, Pearse: "Phosphodiesterase 2A is a major negative regulator of iNOS expression in lipopolysaccharide-treated mouse alveolar macrophages." in: Journal of leukocyte biology, Vol. 96, Issue 5, pp. 907-15, (2015) (PubMed).

Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Kedia, Ückert, Oelke, Sonnenberg, Sohn, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).

Zhai, Chang, Wei, Liu, Leblais, Fischmeister, Ji: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." in: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).

Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

Stephenson, Coskran, Kelly, Kleiman, Morton, ONeill, Schmidt, Weinberg, Menniti: "The distribution of phosphodiesterase 2A in the rat brain." in: Neuroscience, Vol. 226, pp. 145-55, (2013) (PubMed).

Ückert, Oelke, Albrecht, Breitmeier, Kuczyk, Hedlund: "Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)." in: International journal of impotence research, Vol. 23, Issue 5, pp. 206-12, (2012) (PubMed).

Matsuo, Rossier, Kan, Rodriguez: "The wiring of Grueneberg ganglion axons is dependent on neuropilin 1." in: Development (Cambridge, England), Vol. 139, Issue 15, pp. 2783-91, (2012) (PubMed).

Lin, Fretier, Jiang, Vincent: "Nitric oxide signaling via cGMP-stimulated phosphodiesterase in striatal neurons." in: Synapse (New York, N.Y.), Vol. 64, Issue 6, pp. 460-6, (2010) (PubMed).

van der Horst, Morgan, Eaton, Reiss, Tibboel, Thébaud: "Expression and function of phosphodiesterases in nitrofen-induced congenital diaphragmatic hernia in rats." in: Pediatric pulmonology, Vol. 45, Issue 4, pp. 320-5, (2010) (PubMed).

Witzenrath, Gutbier, Schmeck, Tenor, Seybold, Kuelzer, Grentzmann, Hatzelmann, van Laak, Tschernig, Mitchell, Schudt, Rosseau, Suttorp, Schütte: "Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia." in: Critical care medicine, Vol. 37, Issue 2, pp. 584-90, (2009) (PubMed).

Spiessberger, Bernhard, Herrmann, Feil, Werner, Luppa, Hofmann: "cGMP-dependent protein kinase II and aldosterone secretion." in: The FEBS journal, Vol. 276, Issue 4, pp. 1007-13, (2009) (PubMed).

Liu, Fraser, Koos: "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." in: The Journal of comparative neurology, Vol. 516, Issue 1, pp. 36-48, (2009) (PubMed).

Walz, Feinstein, Khan, Mombaerts: "Axonal wiring of guanylate cyclase-D-expressing olfactory neurons is dependent on neuropilin 2 and semaphorin 3F." in: Development (Cambridge, England), Vol. 134, Issue 22, pp. 4063-72, (2008) (PubMed).

Details zu PDE2A

Target: PDE2A (phosphodiesterase 2A, CGMP-Stimulated (PDE2A))

Andere Bezeichnung: PDE2A

Pathways: cAMP Metabolic Process, Synaptic Membrane