Plasma Cell Antikörper

Produktnummer ABIN2743663

Dieser Maus Monoklonal Antikörper detektiert spezifisch Plasma Cell in IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Plasma Cell Antikörper (ABIN2743663)

Target: Plasma Cell

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: LIV3G11

Produktdetails

Spezifität: Human Plasma Cell Marker

Keine Kreuzreaktivität: Ratte (Rattus)

Aufreinigung: Protein G purified

Immunogen: Pancreatic cancer-related mucin.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (0.5 - 1 μg/mL)

Usage: This antibody recognizes an intra-cytoplasmic marker antigen which shows a very high degree of specificity for plasma cells. This marker protein is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm. their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This marker antibody superbly recognizes normal and neoplastic plasma cells in routine formalin/paraffin tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this plasma cell marker antibody is not suitable for staining frozen tissues.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Antigendetails

Target: Plasma Cell