KRT8 Antikörper

Produktnummer ABIN2742508

Dieses Maus Monoklonal-Antikörper erkennt spezifisch KRT8 in WB, IHC, IF, FACS, ELISA, IHC (p) und IP. Er zeigt eine Reaktivität gegenüber Human, Ratte und Zebrafisch (Danio rerio).

Kurzübersicht für KRT8 Antikörper (ABIN2742508)

Target: KRT8 (Keratin 8 (KRT8))

Reaktivität: Human, Ratte, Zebrafisch (Danio rerio)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Klon: H1

Produktdetails anti-KRT8 Antikörper

Spezifität: Human KRT8 / CK8 / Cytokeratin 8

Aufreinigung: Protein G purified

Immunogen: A cytoskeleton preparation containing cytokeratin 8.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (1 - 2 μg/mL)

Usage: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). Cytokeratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibody that recognizes only cytokeratin 8 and 18. Cytokeratin 8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. antibody to Cytokeratin 8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against Cytokeratin 8, 18 and 19). Reportedly, Cytokeratin 8 antibody is useful for the differentiation of lobular ([Character 93]ring-like, perinuclear[Character 94]) from ductal ([Character 93]peripheral-predominant[Character 94]) carcinoma of the breast. ELISA: Order BSA-free format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu KRT8

Target: KRT8 (Keratin 8 (KRT8))

Andere Bezeichnung: KRT8 / CK8 / Cytokeratin 8

Hintergrund: Name/Gene ID: KRT8
Family: Keratin

Synonyms: KRT8, CARD2, CK-8, CYK8, Cytokeratin-8, CK8, K2C8, K8, KO, Keratin-8, Type-II keratin Kb8, Cytokeratin 8, Keratin 8

Gen-ID: 3856