Cytokeratin 19 Antikörper (AA 379-392)

Produktnummer ABIN2742480

Dieser Anti-Cytokeratin 19 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Cytokeratin 19 in WB, IHC, IHC (p), ICC und IHC (fro). Geeignet für Human.

Kurzübersicht für Cytokeratin 19 Antikörper (AA 379-392) (ABIN2742480)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Cytokeratin 19 Antikörper

Bindungsspezifität: AA 379-392

Spezifität: Human KRT19 / CK19 / Cytokeratin 19

Aufreinigung: Immunoaffinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cytokeratin 19 (379-392aa YRSLLEGQEDHYNN). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%), Orangutan, Marmoset, Mouse (93%), Baboon, Rat, Rabbit (86%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ICC (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IHC-P (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

Usage: Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene.The protein encoded by this gene is a member of the keratin family. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Sterile distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.

Details zu Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Andere Bezeichnung: KRT19 / CK19 / Cytokeratin 19

Hintergrund: Name/Gene ID: KRT19

Synonyms: KRT19, CK19, Cytokeratin 19, Cytokeratin-19, Keratin 19, Keratin-19, CK-19, K19, K1CS, Keratin, type I, 40-kd

Gen-ID: 3880