CD34 Antikörper (N-Term)
-
- Target Alle CD34 Antikörper anzeigen
- CD34
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Cynomolgus, Rhesusaffen
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD34 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Spezifität
- Human CD34
- Keine Kreuzreaktivität
- Rind (Kuh), Hund, Ratte (Rattus), Schaf
- Aufreinigung
- Protein G purified
- Immunogen
- A detergent solubilized vesicular suspension prepared from human term placenta.
- Klon
- QBEnd-10
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD34 Primärantikörper
-
-
- Applikationshinweise
-
Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.25 - 0.5 μg/mL)
Usage: This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into three main categories, class I, class II and class III. This is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. CD34 antibody labels > 85 % of angiosarcoma and Kaposi's sarcoma, but with a lower specificity. - Kommentare
-
Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2°C to 8°C.
-
- Target
- CD34
- Andere Bezeichnung
- CD34 (CD34 Produkte)
- Synonyme
- AU040960 antikoerper, CD34 molecule antikoerper, CD34 antigen antikoerper, CD34 antikoerper, Cd34 antikoerper
- Hintergrund
-
Name/Gene ID: CD34
Synonyms: CD34, CD34 Molecule, CD34 antigen - Gen-ID
- 947
-