CD1a Antikörper

Produktnummer ABIN2739072

Der Maus Monoklonal Anti-CD1a-Antikörper wurde für FACS, IF, IHC, WB, ELISA, IHC (p) und IP validiert. Er ist geeignet, CD1a in Proben von Human zu detektieren.

Kurzübersicht für CD1a Antikörper (ABIN2739072)

Target: CD1a

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD1a Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Klon: O10

Produktdetails anti-CD1a Antikörper

Spezifität: Human CD1A

Aufreinigung: Protein G purified

Immunogen: Human thymus cells were used as the immunogen for this CD1a antibody.

Type of Immunogen: Cells

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict Tcell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. CD1a antibody labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibody against TTF-1 and CD5, CD1a antibody is useful in distinguishing between pulmonary and thymic neoplasms since it is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. CD1a antibody is reported to be a new marker for perivascular epithelial cell tumor (PEComa). ELISA: Order BSA-free format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu CD1a

Target: CD1a

Andere Bezeichnung: CD1A

Hintergrund: Name/Gene ID: CD1A

Synonyms: CD1A, CD1, CD1A antigen, a polypeptide, CD1a molecule, FCB6, HTA1, HTa1 thymocyte antigen, R4, T6, CD1a antigen, Cluster of differentiation 1 A

Gen-ID: 909

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process