TP53I3 Antikörper

Produktnummer ABIN2734080

Dieser Maus Monoklonal Antikörper detektiert spezifisch TP53I3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TP53I3 Antikörper (ABIN2734080)

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TP53I3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 3E3

Produktdetails anti-TP53I3 Antikörper

Produktmerkmale: Homo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human TP53I3(NP_671713) produced in HEK293T cell.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:2000,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TP53I3

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Andere Bezeichnung: TP53I3

Hintergrund: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 35.4 kDa

Gen-ID: 9540

NCBI Accession: NM_147184

HGNC: 9540

Pathways: p53 Signalweg