SAMHD1 Antikörper

Produktnummer ABIN2731372

Produktdetails anti-SAMHD1 Antikörper

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reaktivität: Human, Maus, Ratte, Affe, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SAMHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktmerkmale: Homo sapiens SAM domain and HD domain 1 (SAMHD1)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SAMHD1(NP_056289) produced in HEK293T cell.

Klon: 3F5

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB 1:200~500, IHC 1:150, IF 1:100, FLOW 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-SAMHD1 Antikörper (ABIN2731372)

Daddacha, Koyen, Bastien, Head, Dhere, Nabeta, Connolly, Werner, Madden, Daly, Minten, Whelan, Schlafstein, Zhang, Anand, Doronio, Withers, Shepard, Sundaram, Deng, Dynan, Wang, Bindra, Cejka et al.: "SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination. ..." in: Cell reports, Vol. 20, Issue 8, pp. 1921-1935, (2018) (PubMed).

Oh, Ryoo, Park, Kim, Daly, Cho, Ahn: "A central role for PI3K-AKT signaling pathway in linking SAMHD1-deficiency to the type I interferon signature." in: Scientific reports, Vol. 8, Issue 1, pp. 84, (2018) (PubMed).

Jáuregui, Landau: "DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1." in: Scientific reports, Vol. 8, Issue 1, pp. 4153, (2018) (PubMed).

Wittmann, Behrendt, Eissmann, Volkmann, Thomas, Ebert, Cribier, Benkirane, Hornung, Bouzas, Gramberg: "Phosphorylation of murine SAMHD1 regulates its antiretroviral activity." in: Retrovirology, Vol. 12, pp. 103, (2015) (PubMed).

Details zu SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Andere Bezeichnung: SAMHD1 (SAMHD1 Produkte)

Synonyme: CHBL2 antikoerper, DCIP antikoerper, HDDC1 antikoerper, MOP-5 antikoerper, SBBI88 antikoerper, si:dkeyp-44b8.8 antikoerper, E330031J07Rik antikoerper, Mg11 antikoerper, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 antikoerper, SAM domain and HD domain 1 antikoerper, SAM domain and HD domain, 1 antikoerper, SAMHD1 antikoerper, samhd1 antikoerper, Samhd1 antikoerper

Molekulargewicht: 72 kDa

Gen-ID: 25939

NCBI Accession: NM_015474

HGNC: 25939