SAMHD1 Antikörper

Produktnummer ABIN2731369

Produktdetails anti-SAMHD1 Antikörper

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SAMHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktmerkmale: Homo sapiens SAM domain and HD domain 1 (SAMHD1)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.

Klon: 2D7

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB 1:2000, IF 1:100, FLOW 1:100

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-SAMHD1 Antikörper (ABIN2731369)

Jeong, Park, Ahn, Ahn: "Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." in: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).

Hertoghs, van der Aar, Setiawan, Kootstra, Gringhuis, Geijtenbeek: "SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4431-7, (2015) (PubMed).

Pan, Pan, Weng, Zhao, Zhang, Wang, Lv, Jiang, Zheng, Xia: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).

Zhang, Bloch, Nguyen, Kim, Landau: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).

Details zu SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Andere Bezeichnung: SAMHD1 (SAMHD1 Produkte)

Synonyme: CHBL2 antikoerper, DCIP antikoerper, HDDC1 antikoerper, MOP-5 antikoerper, SBBI88 antikoerper, si:dkeyp-44b8.8 antikoerper, E330031J07Rik antikoerper, Mg11 antikoerper, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 antikoerper, SAM domain and HD domain 1 antikoerper, SAM domain and HD domain, 1 antikoerper, SAMHD1 antikoerper, samhd1 antikoerper, Samhd1 antikoerper

Hintergrund: This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. COMPLETENESS: complete on the 3' end.

Molekulargewicht: 72 kDa

Gen-ID: 25939

NCBI Accession: NM_015474

HGNC: 25939