SAMHD1 Antikörper
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- Target Alle SAMHD1 Antikörper anzeigen
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SAMHD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Produktmerkmale
- Homo sapiens SAM domain and HD domain 1 (SAMHD1)
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.
- Klon
- 2D7
- Isotyp
- IgG2b
- Top Product
- Discover our top product SAMHD1 Primärantikörper
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- Applikationshinweise
- WB 1:2000, IF 1:100, FLOW 1:100
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." in: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).
: "SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4431-7, (2015) (PubMed).
: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).
: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).
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Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." in: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).
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- Target
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
- Andere Bezeichnung
- SAMHD1 (SAMHD1 Produkte)
- Hintergrund
- This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. COMPLETENESS: complete on the 3' end.
- Molekulargewicht
- 72 kDa
- Gen-ID
- 25939
- NCBI Accession
- NM_015474
- HGNC
- 25939
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