RGS5 Antikörper

Produktnummer ABIN2730835

Dieses Maus Monoklonal-Antikörper erkennt spezifisch RGS5 in WB, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für RGS5 Antikörper (ABIN2730835)

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RGS5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 1C1

Produktdetails anti-RGS5 Antikörper

Produktmerkmale: Homo sapiens regulator of G-protein signaling 5 (RGS5), transcript variant 1

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human RGS5 (NP_003608) produced in HEK293T cell.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:2000, IHC 1:150, FLOW 1:100

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-RGS5 Antikörper (ABIN2730835)

Adebiyi, Soni, John, Yang: "Lipid rafts are required for signal transduction by angiotensin II receptor type 1 in neonatal glomerular mesangial cells." in: Experimental cell research, Vol. 324, Issue 1, pp. 92-104, (2014) (PubMed).

Özen, Deierborg, Miharada, Padel, Englund, Genové, Paul: "Brain pericytes acquire a microglial phenotype after stroke." in: Acta neuropathologica, Vol. 128, Issue 3, pp. 381-96, (2014) (PubMed).

Pastò, Marchesi, Diamantini, Frasson, Curtarello, Lago, Pilotto, Parenti, Esposito, Agostini, Nitti, Amadori: "PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages." in: PLoS ONE, Vol. 7, Issue 8, pp. e43379, (2012) (PubMed).

Details zu RGS5

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Andere Bezeichnung: RGS5

Hintergrund: This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht: 20.8 kDa

Gen-ID: 8490

NCBI Accession: NM_003617

HGNC: 8490

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling