ITM2B Antikörper

Produktnummer ABIN2723906

Produktdetails anti-ITM2B Antikörper

Target: ITM2B (Integral Membrane Protein 2B (ITM2B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITM2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktmerkmale: Homo sapiens integral membrane protein 2B (ITM2B)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ITM2B (NP_068839) produced in HEK293T cell.

Klon: 1C11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB 1:2000, IHC 1:150, FLOW 1:100

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ITM2B

Target: ITM2B (Integral Membrane Protein 2B (ITM2B))

Andere Bezeichnung: ITM2B (ITM2B Produkte)

Hintergrund: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Molekulargewicht: 30.2 kDa

Gen-ID: 9445

NCBI Accession: NM_021999

HGNC: 9445