TNNI3 Antikörper

Produktnummer ABIN272322

Produktdetails anti-TNNI3 Antikörper

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Fisch, Huhn, Amphibien

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNNI3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse.

Kreuzreaktivität (Details): Also reacts to: skeletal

Aufreinigung: Protein A chromatography

Reinheit: > 90 % pure (SDS-PAGE)

Immunogen: Free human cardiac troponin I

Klon: C5

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 3.5mg/mL (Sigma protein assay kit)

Buffer: PBS, pH 7.4 containing 0,09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Referenzen für anti-TNNI3 Antikörper (ABIN272322)

Laube, Heister, Scholz, Borchardt, Braun: "Re-programming of newt cardiomyocytes is induced by tissue regeneration." in: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4719-29, (2007) (PubMed).

Details zu TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Andere Bezeichnung: Cardiac Troponin I (TNNI3 Produkte)

Synonyme: CMD1FF antikoerper, CMD2A antikoerper, CMH7 antikoerper, RCM1 antikoerper, TNNC1 antikoerper, cTnI antikoerper, CMD1Z antikoerper, CMH13 antikoerper, TN-C antikoerper, TNC antikoerper, TNNC antikoerper, Tn1 antikoerper, TnIc antikoerper, ctnIc antikoerper, XTnIc antikoerper, c-troponin antikoerper, cTNT antikoerper, cmh7 antikoerper, ctni antikoerper, tnnc1 antikoerper, TNNI3 antikoerper, TnI antikoerper, cTNI antikoerper, AI874626 antikoerper, TnC antikoerper, cTnC antikoerper, tncc antikoerper, Tncc antikoerper, troponin I3, cardiac type antikoerper, troponin C1, slow skeletal and cardiac type antikoerper, troponin I, cardiac 3 antikoerper, troponin I type 3 (cardiac) antikoerper, troponin I3, cardiac type S homeolog antikoerper, troponin I3, cardiac type L homeolog antikoerper, cardiac troponin I antikoerper, troponin C, cardiac/slow skeletal antikoerper, TNNI3 antikoerper, TNNC1 antikoerper, Tnni3 antikoerper, tnni3.S antikoerper, tnni3.L antikoerper, tnni3 antikoerper, LOC100462680 antikoerper, Tnnc1 antikoerper

Hintergrund: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3

Gen-ID: 7137

NCBI Accession: NP_000354

UniProt: P19429