TNNI3 Antikörper

Produktnummer ABIN272322

Dieses Anti-TNNI3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TNNI3 in WB und EIA. Geeignet für Human, Maus, Rind (Kuh), Kaninchen, Fisch, Amphibien und Huhn. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für TNNI3 Antikörper (ABIN272322)

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Fisch, Amphibien, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNNI3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: C5

Produktdetails anti-TNNI3 Antikörper

Spezifität: This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse.

Kreuzreaktivität (Details): Also reacts to: skeletal

Aufreinigung: Protein A chromatography

Reinheit: > 90 % pure (SDS-PAGE)

Immunogen: Free human cardiac troponin I

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 3.5mg/mL (Sigma protein assay kit)

Buffer: PBS, pH 7.4 containing 0,09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Referenzen für anti-TNNI3 Antikörper (ABIN272322)

Laube, Heister, Scholz, Borchardt, Braun: "Re-programming of newt cardiomyocytes is induced by tissue regeneration." in: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4719-29, (2007) (PubMed).

Details zu TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Andere Bezeichnung: Cardiac Troponin I

Hintergrund: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3

Gen-ID: 7137

NCBI Accession: NP_000354

UniProt: P19429