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CDH15 Antikörper

Der Kaninchen Polyklonal Anti-CDH15-Antikörper wurde für WB und EIA validiert. Er ist geeignet, CDH15 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN272294

Kurzübersicht für CDH15 Antikörper (ABIN272294)

Target

Alle CDH15 Antikörper anzeigen
CDH15 (M-Cadherin (CDH15))

Reaktivität

Human, Maus, Ratte

Wirt

  • 52
  • 4
  • 3
  • 2
Kaninchen

Klonalität

  • 55
  • 6
Polyklonal

Konjugat

  • 30
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CDH15 Antikörper ist unkonjugiert

Applikation

  • 49
  • 29
  • 21
  • 13
  • 13
  • 9
  • 7
  • 6
  • 6
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Spezifität

    This antibody detects endogenous levels of M-cadherin protein. (region surrounding Ala108)

    Kreuzreaktivität (Details)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Reinheit

    > 95 % pure by SDS-PAGE
  • Applikationshinweise

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1,0 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    DO NOT FREEZE!

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Target

    CDH15 (M-Cadherin (CDH15))

    Andere Bezeichnung

    Cadherin-15

    Hintergrund

    Cadherins are a multigene family of Ca++-dependent cell adhesion molecules. They are transmembrane glycoproteins consisting of an extracellular domain, which mediates Ca++-dependent intercellular adhesion by homophilic interactions, a transmembrane region and a cytoplasmic domain. The extracellular domain is divided into a series of subdomains designated EC1-EC5. Homolgies between different members of the cadherin family are most prominent in the cytoplasmic domain and in EC1 and EC2 and much less so in EC5 of the extracellular domain and in the transmembrane region. The binding properties and specificities of the adhesive function are located in the N-terminal part of the molecules. Four members of the cadherin family have been identified and molecularly cloned from mammalian cells. These include the neuronal (N), epithelial (E), placental (P) and muscle (M) cadherins. M-cadherin is not found in fibroblasts but is expressed at low level in myoblasts and is upregulated following induction of myotube formation, suggesting a specific function in skeletal muscle cell differentiation.Synonyms: CDH14, CDH15, CDH3, Cadherin M, Cadherin-14, M-Cadherin, Muscle cadherin

    Molekulargewicht

    approx. 91 kDa

    Gen-ID

    1013

    NCBI Accession

    NP_004924

    UniProt

    P55291
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