ADD3 Antikörper

Produktnummer ABIN272287

Produktdetails anti-ADD3 Antikörper

Target: ADD3 (Adducin 3 (Gamma) (ADD3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Adducin γ protein. (region surrounding Pro452)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu ADD3

Target: ADD3 (Adducin 3 (Gamma) (ADD3))

Andere Bezeichnung: gamma-Adducin (ADD3) (ADD3 Produkte)

Synonyme: gamma-adducin antikoerper, add3 antikoerper, MGC89418 antikoerper, ADD3 antikoerper, DKFZp459E0630 antikoerper, ADDL antikoerper, AI463285 antikoerper, R75380 antikoerper, adducin 3 (gamma) antikoerper, adducin 3 antikoerper, adducin 3 L homeolog antikoerper, ADD3 antikoerper, add3 antikoerper, add3.L antikoerper, Add3 antikoerper

Hintergrund: Adducins are a family of cytoskeleton proteins encoded by three genes (α, β and γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain andhematopoietic tissues, such as bone marrow in humans, and spleen in mice.Synonyms: ADDL, Adducin 3, Adducin-like protein 70

Molekulargewicht: approx. 82 kDa

Gen-ID: 120

NCBI Accession: NP_001112

UniProt: Q9UEY8