YBX2 Antikörper

Produktnummer ABIN272262

Der Kaninchen Polyklonal anti-YBX2 Antikörper (ABIN272262) detektiert spezifisch YBX2 in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für YBX2 Antikörper (ABIN272262)

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YBX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-YBX2 Antikörper

Spezifität: This antibody detects endogenous levels of MSY2 protein. (region surrounding Gly311)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu YBX2

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Andere Bezeichnung: YBX2

Hintergrund: Contrin (MSY2 in mouse) and YB-2 (MSY3/4 in mouse) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation.Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins. The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues. MSY2 (Contrin) is a expressed in testis and ovary, where it may repress translation of parental mRNA. The gene encoding human Contrin maps to chromosome 17p11.2-13.1. MSY3/4 (YB-2) is also known as DNA binding protein A and is highly expressed in testis, heart and muscle. Contrin and YB-2 bind to the consensus sequence 5'-UCCAUCA-3' contained in the Y-box element.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2

Molekulargewicht: approx. 38 kDa

Gen-ID: 51087

NCBI Accession: NP_057066

UniProt: Q9Y2T7

Pathways: Chromatin Binding