HDAC1 Antikörper
Kurzübersicht für HDAC1 Antikörper (ABIN2722470)
Target
Alle HDAC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Homo sapiens histone deacetylase 1 (HDAC1)
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Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human HDAC1 (NP_004955) produced in HEK293T cell.
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Isotyp
- IgG1
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Applikationshinweise
- WB 1:500, IF 1:100, FLOW 1:100
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Kommentare
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The concentration of the product may vary between diferrent lots.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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Andere Bezeichnung
- HDAC1
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Hintergrund
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
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Molekulargewicht
- 54.9 kDa
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Gen-ID
- 3065
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NCBI Accession
- NM_004964
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HGNC
- 3065
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Pathways
- Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
Target
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